1. Organs for research and education
Matthew Bock

2. When are organs used for research?
Only after they have been determined unsuitable for transplant

3. What makes an organ unsuitable for transplant?
Performance
Condition

4. Performance Kidneys Liver Pancreas Heart Lungs Creatinine AST/ALT A1C
Troponin, Echo
Lungs
X-ray, PO2

5. Condition
Fatty pancreas
Polycystic kidney
Fibrotic or fatty liver

6. If we can’t transplant…
There is still an option…
Research consent

9. Page 2 (back) of consent form

10. Page 2 (back) of consent form

11. Research consent for transplanted organs
Liver study
Biopsy
Lung study
Bronch washings and blood ample
Kidney study

12. Order
1st - Transplant
2nd- In-house research
3rd - National

13. Order
1st - Transplant
2nd- In-house research
3rd - National

14. Order 1st - Transplant 2nd- In-house research 3rd - National
Pancreas islet cells
3rd - National

15. Order
1st - Transplant
2nd- In-house research
3rd - National

16. Order
1st - Transplant
2nd- In-house research
3rd - National
NDRI
IIAM

17. Who are NDRI and IIAM? NDRI, National disease research interchange
IIAM, International Institute for the Advancement of Medicine
Both are 501c non-profit

18. Heart
Heart, Arteries and Veins Medical investigators use the human heart to learn about the development of atherosclerosis in coronary arteries

19. Kidneys
Renal tissues is used to study the toxicity of anti-cancer therapies and to study the safe concentrations of other drugs in development

20. Lungs
Research into chronic obstructive pulmonary disease (COPD), cystic fibrosis, asthma, emphysema and allergies

21. Pancres
Diabetes researchers rely on pancreatic tissues to explore the regulation of insulin production, to identify the genetic components of the disease and for toxicity studies on new compounds.

22. Liver Hepatocyte cell isolation for transplantation
Human model for drug interaction, toxicity and metabolism testing

23. Education
Whole body donation