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Protein S human.

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Presentation on theme: "Protein S human."— Presentation transcript:

1 Protein S human

2 Description : Protein S (also known as S-Protein) is a vitamin K-dependent plasma glycoprotein synthesized in the liver. In the circulation, Protein S exists in two forms: a free form and a complex form bound to complement protein C4b-binding protein (C4BP). In humans, protein S is encoded by the PROS1 gene.

3 Indication : To prevent coagulation and stimulating fibrinolysis.

4 Mechanism of Action : Categories : Cofactor for activated protein C.
Anticoagulant plasma protein.

5 Brands : Protein S human
Description : Protein S is a single chain vitamin K-dependent protein which is thought to function in both the coagulation and complement cascades (1,2). Approximately 60% of protein S circulating in plasma is complexed to C4b binding protein (C4BP). It has been suggested that g-carboxyglutamic acid (gla) dependent binding of protein S to negatively charged phospholipids may function to concentrate C4BP at cell surfaces following injury.

6 References : http://www. haemtech


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