1. Copyright © 2003 American Medical Association. All rights reserved.
From: A 12-Week, Double-blind Comparison of Olanzapine vs Haloperidol in the Treatment of Acute Mania
Arch Gen Psychiatry. 2003;60(12): doi: /archpsyc
Figure Legend:
Patient flowchart.
Date of download: 11/4/2017
Copyright © 2003 American Medical Association. All rights reserved.

2. Copyright © 2003 American Medical Association. All rights reserved.
From: A 12-Week, Double-blind Comparison of Olanzapine vs Haloperidol in the Treatment of Acute Mania
Arch Gen Psychiatry. 2003;60(12): doi: /archpsyc
Figure Legend:
Time to switch to depression for patients who were not clinically depressed at baseline (21-item Hamilton Rating Scale for Depression [HAMD-21] score ≤8). Time to switch into depression (HAMD-21 score ≥15) was significantly longer (log-rank test χ21 = 4.1, P = .04) for the olanzapine group (dashed line) compared with the haloperidol group (solid line). During the 12-week period, 22 haloperidol- and 12 olanzapine-treated patients switched into depression. The number of patients who experienced a switch to depression by days 15, 30, and 60 were 3, 9, and 18 for the haloperidol group and 1, 3, and 8 for the olanzapine group, respectively.
Date of download: 11/4/2017
Copyright © 2003 American Medical Association. All rights reserved.