1. Self-assembly of Peptide Nanotubes
NSF Site Visit
June 10, 2004
Shuguang Zhang
Center for Biomedical Engineering, Center for Bits & Atoms
Massachusetts Institute of Technology
Cambridge, MA 02139, USA

2. Peptide surfactant-detergents

3. Steve Santoso, NanoLetters, 7/2002
Sylvain Vauthey, PNAS, 4/2002,
Steve Santoso, NanoLetters, 7/2002
Geoffrey von Maltzahn, Langmuir, 5/2003

4. + lipid bilayer solubilized membrane proteins detergent micelles
+ monomers +
lipid-detergent
micelles

5. The energy harvest systems are embedded in membranes

6. Peptide detergents stabilized photosystem I for long-term
650
675
700
725
750
775
800
0.0
0.2
0.4
0.6
0.8
1.0
Fluorescent intensity [a.u.]
Wavelength (l) [nm]
diluted
solution
A6K
day 7
day 21
670
690 1
l [nm]
h [a.u.]
Absorption [a.u.]
Das, et al., NanoLetters, June 2004

7. Das, et al., NanoLetters, June 2004
Peptide detergents stabilized photosystem I generate current & voltage
700
750
800
850
900
950
0.0
0.2
0.4
0.6
0.8
1.0
Quantum efficiency [a.u.]
Wavelength [nm]
Absorption [a.u.]
-0.05
0.05
-0.4
-0.2
J [mA/cm2]
V [V]
dark
light w.
peptides
light - no peptides
(l = 808nm,
10 W/cm2)
Das, et al., NanoLetters, June 2004