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Heparin Infusion Calculations
Chapter 19 Heparin Infusion Calculations
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Heparin Potent anticoagulant that inhibits new blood clot formation or extension of existing blood clots
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Heparin Doses expressed in USP units May be administered:
Subcutaneously By IV infusion By IV bolus
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Heparin Vial and manufactured infusions usually have heparin printed in red on label Due to critical action and potential adverse effect of bleeding Requires frequent check of coagulation times
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Heparin Available in several vial dosage strengths
Labels must be carefully read and rechecked
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Subcutaneous Injections
Requires deep injection Should not be aspirated after injecting needle Should not be massaged after medication injected
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Heparin IV Infusions May be prescribed by mL/hr flow rate or by units/hr to infuse Must use EID or microdrip Preferably EID Requires dedicated IV line
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Heparin IV Infusions Heparin dosages based on protocols, clotting time, and/or body weight in kg Due to changes in clotting times during heparin infusion, rate may need to be changed or titrated before infusion complete
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Calculation Example 1 Prescription for heparin to infuse at 1000 units/hr from solution of 20,000 units in 500 mL D5W Calculate mL/hr flow rate
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Using DA = 25 mL/hr
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Calculation Example 2 Prescribed for heparin to infuse 800 units/hour from solution of 40,000 units in 1000 mL D5W Calculate mL/hr flow rate
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Using DA mL 1000 mL 800 units hr 40,000 units 1 hr ,000 1 = 20 mL/hr
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Calculation Example 3 IV of 1000 mL containing 40,000 units is infusing at 30 mL/hr Calculate number of units infusing per hour
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Using DA units 40,000 units 30 mL hr 1000 mL 1 hr 40, = 1200 units/hr
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Heparin Flush Dosage Dosage strengths of heparin flush
10 to 100 units/mL 10 units/mL used for peripheral access flush 100 units/mL used for central venous access flush Should never exceed 100 units
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