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Algorithm for the metabolic management of type 2 diabetes mellitus; reinforce lifestyle interventions at every visit and check hemoglobin A1c every 3 months until A1c is less than 7% (0.07; 53 mmol/mol Hb) and then at least every 6 months. The interventions should be changed if A1c is greater than or equal to 7% (0.07; 53 mmol/mol Hb). αSulfonylureas other than glybenclamide (glyburide) or chlorpropamide. bInsufficient clinical use to be confident regarding safety. See Figure 43–1 for initiation and adjustment of insulin. (CHF, congestive heart failure; GLP-1, glucagon-like peptide-1.) (Nathan DM, Buse JB, Davidson MB, et al. Medical management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy: A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2009;32:193–203; With permission.) Source: Endocrinologic Disorders, Pharmacotherapy Principles & Practice, 3e Citation: Chisholm-Burns MA, Wells BG, Schwinghammer TL, Malone PM, Kolesar JM, DiPiro JT. Pharmacotherapy Principles & Practice, 3e; 2013 Available at: Accessed: November 05, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved
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