1. X Chromosome Inactivation

2. X Chromosome Inactivation
-the process by which one of the x chromosomes in female mammals is inactivated

3. Lyonization = skewed X inactivation
XX-distribution of active X

4. During Development

5. During Development

6. Movie Youtube search X chromosome inactivation

7. Implications of Inactivation

8. Cat Cloning
Daughter
Mother

9. Single Nucleotide Polymorphisms SNPs
-a DNA nucleotide variation occurring in the genome between two members of the same species

10. Occurrance in Humans -1 in 1000 bases, 0.1%
-3 to 10 million SNPs in the
human genome

11. SNP Movie Search “What are SNPs?”
“Biomarkers in human health care”

12. Importance of SNPs

13. Treatment of Diseases

14. Cancer Treatment

15. Population Studies

16. Restriction Fragment Length Polymorphism (RFLP)
-Restriction Enzymes