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A contribution to the chemical profiling of 3,4-methylenedioxymethamphetamine (MDMA) tablets  Pascal Gimeno, Fabrice Besacier, Huguette Chaudron-Thozet,

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Presentation on theme: "A contribution to the chemical profiling of 3,4-methylenedioxymethamphetamine (MDMA) tablets  Pascal Gimeno, Fabrice Besacier, Huguette Chaudron-Thozet,"— Presentation transcript:

1 A contribution to the chemical profiling of 3,4-methylenedioxymethamphetamine (MDMA) tablets 
Pascal Gimeno, Fabrice Besacier, Huguette Chaudron-Thozet, Josiane Girard, Alain Lamotte  Forensic Science International  Volume 127, Issue 1, Pages 1-44 (June 2002) DOI: /S (02)

2 Fig. 1 Ei/full scan impurity profile of sample Ref1.
Forensic Science International  , 1-44DOI: ( /S (02) )

3 Fig. 2 Ei/full scan impurity profile of sample Ref2.
Forensic Science International  , 1-44DOI: ( /S (02) )

4 Fig. 3 Ei/full scan impurity profile of sample S1.
Forensic Science International  , 1-44DOI: ( /S (02) )

5 Fig. 4 Ei/full scan impurity profile of sample S2.
Forensic Science International  , 1-44DOI: ( /S (02) )

6 Fig. 5 Ei/full scan impurity profile of sample S3.
Forensic Science International  , 1-44DOI: ( /S (02) )

7 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

8 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

9 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

10 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

11 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

12 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

13 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

14 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

15 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

16 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

17 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

18 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

19 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

20 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

21 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

22 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

23 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

24 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

25 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

26 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

27 Fig. 6 Electron ionization mass spectrum of impurity peaks 2, 3, 7, 8, 9, 11–26. Forensic Science International  , 1-44DOI: ( /S (02) )

28 Fig. 7 Peak #2-Ci+/MS–MS confirmation on M+ molecular ion (m/z=122).
Forensic Science International  , 1-44DOI: ( /S (02) )

29 Fig. 8 Peak #13-Ci+/MS–MS confirmation on MH+ molecular ion (m/z=180).
Forensic Science International  , 1-44DOI: ( /S (02) )

30 Fig. 9 Peak #16-Ci+/MS–MS confirmation on MH+ molecular ion (m/z=180).
Forensic Science International  , 1-44DOI: ( /S (02) )

31 Fig. 10 Peak #23-Ci+/MS–MS confirmation on MH+ molecular ion (m/z=210). Forensic Science International  , 1-44DOI: ( /S (02) )

32 Fig. 11 Peak #26-Ci+/MS–MS confirmation on MH+ molecular ion (m/z=222). Forensic Science International  , 1-44DOI: ( /S (02) )

33 Fig. 12 Peak #11-Ci+/full scan mass spectrum.
Forensic Science International  , 1-44DOI: ( /S (02) )

34 Fig. 13 MDMA synthesis from MDP2P by reductive amination.
Forensic Science International  , 1-44DOI: ( /S (02) )

35 Fig. 14 MDMA by-products obtained from MDP2P.
Forensic Science International  , 1-44DOI: ( /S (02) )

36 Fig. 15 MDMA by-products obtained from piperonal.
Forensic Science International  , 1-44DOI: ( /S (02) )

37 Fig. 16 Safrole/isosafrole impurities modified during MDMA synthesis.
Forensic Science International  , 1-44DOI: ( /S (02) )

38 Fig. 17 Cosine function values for linked samples.
Forensic Science International  , 1-44DOI: ( /S (02) )

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