1. Hepatitis Studies Shyam Kottilil M.D., Ph.D.
Laboratory of Immunoregulation
National Institute of Allergy and Infectious
Diseases
National Institutes of Health
Department of Health and Human Services
Bethesda, MD

2. Hepatitis C and HIV coexist in the US
IVDU 5
100
HCV
90% 4 80 3 60
Number affected (millions)
Percentage
All HIV+ 2 40
33%
HIV 1 20
Population
Population
Sulkowski MS, Mast EE, Seeff, LB et al. Hepatitis C Virus Infection as an Opportunistic Disease in Persons infected with Human Immunodeficiency Virus. Clin Infect Dis. 2000;30:

3. Washington, D.C. Our Nation’s Capital
3%=18000 HIV+
1.8%=12000 HCV+ 3

4. Numbers found below each ward refer to the rate of newly reported
Establishment of Hepatitis Clinics
Average Incidence Rate
per 100,000 Population
25.1 – 50.0
50.1 – 75.0
75.1 – 100.0
100.1 – 125.0
Numbers found below each ward refer to the rate of newly reported
HIV cases per 100,000 population. Rates were calculated using 2000 Census data.
For 16% of cases, ward information was not available and therefore not displayed on this map. 4

5. Hepatitis Treatment Protocols-DC-PFAP
TLR7 Phase 1
HCV-DAA
Natural History
GS-7977+RBV
Anti-fibrosis
Anti-fibrosis
HCV DAA Tx
Jan
June
Sept
June
Mar
Dec
Mar
Sept
Anti-fibrosis
Peg+RBV+PI (Boc)
IFN and RBV FREE Tx
TLR7 PHASE 1
HCV-DAA

6. Most Effective HIV Program Most Effective Hepatitis Program
Washington, D.C. Our Nation’s Capital
Most Effective HIV Program
Most Effective Hepatitis Program 6