1. Negative Pressure Wound Therapy (NPWT) : Principles and Applications
A-Young Lee (李雅永) Ph.D.
Academic support, Daewoong Pharmaceutical

2. Ancient Cupping Therapy
Ge Hong ( A.D)
“Acupuncture and cupping, more than half of the ills cured”

3. Evolution of NPWT Foam KulaVAC® -Daewoong 1995: Wound VAC®– KCI
1947, Russia
Post-op exudate management
Wall Suction & Gauze
Foam
KulaVAC® -Daewoong
EZ Care™ - Smith & Nephew
Engenex® (Boehringer Wound Systems) – ConvaTec
Genadyne A4 – Genadyne Biotechnologies Inc.
Kalypto - Kalypto Medical
Medela® - Invia
MoblVac® - Ohio Medical
Prodigy™ - Premco Medical Systems, Inc.
Prospera PRO-I™ & PRO-II™ Systems – Medica
Renasys – Smith & Nephew
Svedman™ & Sved™ Systems - Innovative Therapies
Venturi™ System - Talley Group
1952
Closed suction
used prophylactically
to reduce Post-op complications

4. NPWT on Wound Healing Promotes Granulation tissue formation
Provide moist wound environment
Removes Exudate
Infectious materials
Mechanical/ Biological
Forces
Angiogenesis & ↑perfusion
Cell migration & proliferation
Promotes Granulation tissue formation

5. Composition of KulaVAC®
Components
Foam Dressing (Three Different Sizes)
Film Dressing
Accessories (Suction Head, Tubing with Connectors and Clamp)

6. Features of KulaVAC® Polyurethane Foam
hydrophobic, prevents
Contamination from
exudate.
Prevents ingrowth of granulation tissue
Pore size : μm

7. KulaVAC® Bridge

8. KulaVAC® Silver

9. 2. The world’s first cyclic Mode of Curasys®
Features of Curasys®
1. Portability
Weight 890g
Up to 12 hours of battery life
A/C or battery operational
2. The world’s first cyclic Mode of Curasys®
Increased vascular Perfusion
Faster wound closure
Reduced pain

10. KulaVAC® on Various Indications
Dehisced Wound
DM Foot
Pressure Ulcer
Trauma

11. KulaVAC® on Various Indications
Skin Graft
Open Abdomen
Burn

12. KulaVAC® Publications

13. KulaVAC® Publications

14. KulaVAC® Publications
Intermittent mode
Cyclic mode

15. KulaVAC® Clinical Trial on Trauma
Effects of Incisional NPWT
on High-energy Foot & Ankle Trauma
- A Prospective, Multicenter, Randomized Controlled Trial-
High risk of Wound dehiscence, Marginal necrosis, Infection
Infection/Dehiscence rate
Pilon Fx: 5~40%
Calcaneal Fx: 0~25%
(본 연구는 CG Bio의 후원으로 이루어졌음.)