1. CYP2D6 and CYP2C19 genotypes and amitriptyline metabolite ratios in a series of medicolegal autopsies 
Anna Koski, Johanna Sistonen, Ilkka Ojanperä, Merja Gergov, Erkki Vuori, Antti Sajantila 
Forensic Science International 
Volume 158, Issue 2, Pages (May 2006)
DOI: /j.forsciint
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2. Fig. 1
Outline of Phase I metabolism of amitriptyline (AT). Boldface arrows represent the major hydroxylation pathways catalyzed by CYP2D6. Open arrows represent the major demethylation pathways catalyzed by CYP2C19. EHAT, (E)-10-hydroxyamitriptyline; EHNT, (E)-10-hydroxynortriptyline; NT, nortriptyline; NNT, demethylnortriptyline; ZHAT, (Z)-10-hydroxyamitriptyline; ZHNT, (Z)-10-hydroxynortriptyline. N-oxide formation not shown.
Forensic Science International  , DOI: ( /j.forsciint )
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3. Fig. 2
Logarithmic median metabolite ratios plotted against the number of functional copies of CYP2D6 (left) or CYP2C19 (right). For abbreviations, see Fig. 1.
Forensic Science International  , DOI: ( /j.forsciint )
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