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Chronic pancreatitis. A, Note the loss of pancreatic parenchyma and its replacement with fibrosis. Chronic pancreatitis is not an immediately life-threatening condition as is acute pancreatitis; however, it can lead to secondary diabetes mellitus and malabsorption, depending upon its extent. B, Note the loss of pancreatic glandular parenchyma and its replacement with fibrosis (the glandular parenchyma should be back to back). The islets are resistant to the changes and, in cases of chronic pancreatitis, only clusters of pancreatic islets may be present among the fibrosis. Hematoxylin and eosin, 40×. Source: Chapter 15. Pathology of the Liver, Gallbladder, and Pancreas, Pathology: The Big Picture Citation: Kemp WL, Burns DK, Brown TG. Pathology: The Big Picture; 2008 Available at: Accessed: November 06, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved
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