1. Technical Comments on the Brochure and updates on EDC work
AG on EDCs meeting 25-26th September 2015
Derek Muir
Research Scientist, Environment Canada
Comments on the Brochure
While the “EDCs and alligators” is a nice example there are some well known confounding effects eg diet, thiamine deficiency etc
A stronger example is the study by Kidd et al PNAS 2007 on the collapse of a fish population after exposure to a synthetic estrogen
Also synthetic estrogens in wastewaters and feminization of fish
Another well known example is the feminization of fish downstream of pulp and paper mill effluents ie could be alkylated PAHs but not estrogens
In general there could be more emphasis on chemicals in consumer products (phthalates, BPA) and pharmaceuticals, and less on POPs
Under “moving forward” I think the Stockholm Convention, which addresses many of the chemicals listed in this brochure, should be highlighted
By taking global action on POPs, exposures to EDCs are being addressed to some extent (depending on their relative importance as EDCs)

2. Assessment Activities related to EDCs that may be of interest
(I’ve been involved as a contributor and co-leader in those listed below)
Arctic Monitoring and Assessment Program (AMAP) – new assessment reports in prep
Temporal trends of POPs (early 2016)
Contaminants of Emerging Concern in the Arctic (mid-2016)
Effects of contaminants (POPs and mercury) on Arctic wildlife (2017)
Contact: Simon Wilson
Global Monitoring Program on POPs
2nd Global Monitoring Report (latest draft Sept 2015) – has a good summary of POPs data including human exposure (due to be published in early 2016)
Canadian Arctic Contaminants Assessment report (“POPs in Canada’s North ”)
Has time trend data for POPs and “emerging” contaminants which may be of interest in terms of EDC exposures of wildlife
Available at:   – where it is downloadable from the “publications” link.

3. So Many Questions: Just the Tip of the Iceberg!
An environmental analytical chemistry perspective on EDCs (one of my own research interests)
Tentatively identified
Target analytes
Identification
Identified
Artifacts
Detection
Separation
Resolved
Unresolved
The analysis of target analytes can be viewed as a top-down approach that only scratches the surface of the number of chemicals that can be measured
Extraction
Extractables
Non-Extractables
Range of toxicity and concentration
Spectrum of chemicals (>100,000)
Graphic redrawn from Daughton (US EPA) 2005