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Proton magnetic resonance spectroscopy of the brain of a 5-year-old Japanese boy with SLS. Left panel is T2-weighted MRI showing periventricular white.

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Presentation on theme: "Proton magnetic resonance spectroscopy of the brain of a 5-year-old Japanese boy with SLS. Left panel is T2-weighted MRI showing periventricular white."— Presentation transcript:

1 Proton magnetic resonance spectroscopy of the brain of a 5-year-old Japanese boy with SLS. Left panel is T2-weighted MRI showing periventricular white matter disease. Right panel is proton magnetic resonance spectrum image of the region of the frontal lobe indicated by a rectangle in the left panel. The filled arrows point to an abnormal peak at 1.3 ppm corresponding to an unidentified lipid. The open arrow identifies a second unidentified lipid at 0.9 ppm. Cho = choline, PCr = phosphocreatine, Cr = creatine, NAA = N-acetyl aspartate. (This figure is provided by Dr. Toshiyuki Mano, Department of Pediatrics, Osaka University, Osaka, Japan, and reprinted by permission of the American Journal of Neuroradiology.55 ) Source: Sjögren-Larsson Syndrome: Fatty Aldehyde Dehydrogenase Deficiency, The Online Metabolic and Molecular Bases of Inherited Disease Citation: Valle D, Beaudet AL, Vogelstein B, Kinzler KW, Antonarakis SE, Ballabio A, Gibson K, Mitchell G. The Online Metabolic and Molecular Bases of Inherited Disease; 2014 Available at: Accessed: November 07, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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