1. Fig. 1 (A) The figure shows the placement of the 1 cm thick sagittal slices in ³¹P-MRS. According to their position, slices were assigned to contain mainly cortical tissue, mainly white matter or mixed grey and white matter. Below the scan a typical ³¹P-spectrum with the peaks for phosphodiesters (PDE), inorganic phosphate (Pi), phosphomonoesters (PME), phosphocreatine (PCr) and the three peaks for ATP is shown. (B) The figure shows where the voxels were placed for ¹H-MRS. The size of the voxels was 3 × 3 × 2 cm³. The voxel were placed at the level of the basal ganglia to include as much white matter as possible and to minimize contribution from CSF. A typical ¹H-spectrum with peaks for N-acetyl-aspartate (NAA), choline (Cho) and creatine (Cre) is shown below the scan.
From: Association between cortical metabolite levels and clinical manifestations of migrainous aura: an MR-spectroscopy study
Brain. 2007;130(12): doi: /brain/awm165
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