1. The mutagen nitrous acid replaces amino groups with keto groups, thus converting cytosine into uracil or adenine into hypoxanthine. The pairing of these modified bases leads to a mutation when the strand replicates. (Reprinted with permission from Brooker RJ: Genetics: Analysis & Principles, 3rd ed. New York: McGraw-Hill, 2008.)
Source: Mutation, Medical Genetics: An Integrated Approach
Citation: Schaefer G, Thompson, Jr. JN. Medical Genetics: An Integrated Approach; 2017 Available at: Accessed: November 07, 2017
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