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Published byDerick Ellis Modified over 6 years ago
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Development and validation of a liquid chromatography–tandem mass spectrometry assay for hair analysis of atomoxetine and its metabolites: Application in clinical practice Esther Papaseit, Emilia Marchei, Claudia Mortali, Gemma Aznar, Oscar Garcia-Algar, Magi Farrè, Roberta Pacifici, Simona Pichini Forensic Science International Volume 218, Issue 1, Pages (May 2012) DOI: /j.forsciint Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions
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Fig. 1 LC–MS/MS chromatogram of drug-free hair sample spiked at the low quality control concentration (0.3ng/mg) for 4-hydroxyatomoxetine, N-desmethylatomoxetine and atomoxetine and spiked with 50ng/mg for risperidone, sertraline and carbamazepine. Duloxetine (IS) is 5ng/mg. Forensic Science International , 62-67DOI: ( /j.forsciint ) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions
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Fig. 2 LC–MS/MS chromatogram of a hair sample extract containing: 0.49ng/mg 4-hydroxyatomoxetine, 0.64ng/mg risperidone, 0.90ng/mg atomoxetine, 29.81ng/mg sertraline, and 5ng/mg duloxetine (IS). Forensic Science International , 62-67DOI: ( /j.forsciint ) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions
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