1. Volume 96, Issue 1, Pages 114-119 (July 1989)
Randomized Double-Blind, Multicenter Study of Prostaglandin E1 in Patients with the Adult Respiratory Distress Syndrome 
Roger C. Bone, M.D., F.C.C.P., Gus Slotman, M.D., Richard Maunder, M.D., F.C.C.P., Henry Silverman, M.D., F.C.C.P., Thomas M. Hyers, M.D., F.C.C.P., Morris D. Kerstein, M.D., Joseph J. Ursprung, M.D. 
CHEST 
Volume 96, Issue 1, Pages (July 1989)
DOI: /chest
Copyright © 1989 The American College of Chest Physicians Terms and Conditions

2. Figure 1
Survival curve for the 50 PGE1-treated patients and 50 placebo-treated patients. Survival days are counted from the start of infusion. The + indicates the last date of contact for individual patients—they are counted as survivors.
CHEST  , DOI: ( /chest )
Copyright © 1989 The American College of Chest Physicians Terms and Conditions

3. Figure 2
Mean change of systemic vascular resistance index from baseline (study day 0.). In this and subsequent figures, PGE1 (•) or placebo (○) was infused for 7 days or until the patient died. The reading on study day 0 is just prior to the start of infusion and on study day 8 is a post-infusion value. The abscissa is the mean change from baseline for all patients surviving that day. Vertical bars represent standard error of the mean.
CHEST  , DOI: ( /chest )
Copyright © 1989 The American College of Chest Physicians Terms and Conditions

4. Figure 3
Mean change of mean arterial pressure from baseline. In this and subsequent figures* = p<0.05 and ** = p<0.01 between the two treatment groups. PGE1 (•) or placebo (○), as in Figure 2.
CHEST  , DOI: ( /chest )
Copyright © 1989 The American College of Chest Physicians Terms and Conditions

5. Figure 4
Mean change of cardiac output from baseline. PGE1 (•) or placebo (○), as in Figure 2.
CHEST  , DOI: ( /chest )
Copyright © 1989 The American College of Chest Physicians Terms and Conditions

6. Figure 5
Mean change of pulmonary vascular resistance index from baseline. PGE1 (•) or placebo, as in Figure 2.
CHEST  , DOI: ( /chest )
Copyright © 1989 The American College of Chest Physicians Terms and Conditions

7. Figure 6
Mean change of oxygen availability index from baseline. O2Avl = CI(CaO2). CI = cardiac index. PGE1 (•) or placebo (○), as in Figure 2.
CHEST  , DOI: ( /chest )
Copyright © 1989 The American College of Chest Physicians Terms and Conditions

8. Figure 7
Mean change of oxygen consumption index from baseline. Vo2I=CI(CaO2-CvO2). PGE1 (•) or placebo, as in Figure 2.
CHEST  , DOI: ( /chest )
Copyright © 1989 The American College of Chest Physicians Terms and Conditions

9. Figure 8
Relationship of mean change of oxygen consumption to oxygen availability at each study day through day 8. PGE1 (•) or placebo, as in Figure 2.
CHEST  , DOI: ( /chest )
Copyright © 1989 The American College of Chest Physicians Terms and Conditions