1. Presentation of the health pole Philippe Laniece (IMNC)
P2IO Scientific Council , June

2. Adequation of the health pole in P2IO and main challenges
Historical tradition of physics
Increasing societal needs + interdisciplinarity challenges
Example: major research center such as Brookhaven (BNL), Berkeley (LBL), Jefferson Lab
348 | VOL.8 NO.4 | APRIL 2011 | nature methods
In that context, two specific/technological challenges related to nuclear physics field are at this time expected:
Increasing the sensitivity and resolution of molecular imaging (multimodal imaging)
Improving methods for radiation therapy (accelerators, dose calculations, modeling)

3. P2IO strengths in the domain
Good interdisciplinary research = monodisciplinary excellence + bridging disciplinary gaps
P2IO combines outstandingly these assets
3 pillars
Oncology
World class skills
and specific know how
Preclinical and
Clinical local
facilities
➙ accelerators
➙ detectors
➙ cryogenics
➙ computing
➙ space techniques
Neuroscience
Interfaces
National and International Preclinical and Clinical Centers

4. Main projects in which P2IO labs are involved in terms of know-how and applications

5. Main projects in which P2IO labs are involved
Specific Staff: 50
Technical staff: 30

6. P2IO actions for health theme
CaLIPSO: new generation of PET scanner dedicated to neurological imaging
Aims:
Improve the sensitivity and resolution of PET scanner
Develop a new dynamic imaging tool dedicated to neuroscience
Propose an alternative to PET detection for in vivo monitoring in hadrontherapy
Expected performances: sensitivity 10 %, spatial resolution 1 mm, high solid angle
Preliminary module of the Calispo detector
double detection:
Signal:  Scintillation 
trigger et timing
Signal: Ionisation
Energy measurement and 3D Position
Photodetector
(trigger and timing)
Scintillating
photons
metal pixels deposit (stable metal) and conception of resistive layer by implantation
simulation of CaLIPSO detector (plateform GATE)
Ionizing chamber
Pixelated plan dedicated to charge collection
TMBi

7. Conclusion Aims Means Actions
Explore :
biological issues: specific neurophysiological and neuropathological mechanisms
clinical issues: new strategies for cancer treatment and therapy
Means
Transform :
scientific and technical high level knowledges and skills of P2IO physics for supporting health care
Actions
Structure : see perspectives

8. Actions Short-term priorities 2012-2014 Long-term priorities 2012-2017
Support in unifying local projects: Calipso, SipMed, …
Develop an operational network: introduction of the first ‘health center’ workshop strongly connected to the local biomedical facilities
Involvement in french biomedical facilities and networks: « Infrastructures Nationales en Biologie et Santé »: France Life Imaging and France Hadron, GDR
Long-term priorities
promotion of unifying local projects: support of 1 project/year
Consolidation of the health pole network with biomedical platforms
Organisation of a dedicated conference (national or international)
integration to the physics-medicine Idex framework: support to the ‘health pole vallée’ project