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What is the difference between MITOSIS and MEIOSIS?
ONE LAST TIME : What is the difference between MITOSIS and MEIOSIS? HOW ARE THEY SIMILAR? HOW ARE THEY DIFFERENT?
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Mitosis and Meiosis are both forms of dividing the nucleus
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QUIZ Question 1 I * * P * * * M * A * T * * * C *
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Mitosis Meiosis WHAT it is used for How many daughter cells Are the daughters identical to the parent? If the parent is diploid with 16 chromosomes, what will the daughter be? Does the DNA need to replicate before division? Does crossing over occur?
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Mitosis Cell Division Used for growth and repair
Occurs in somatic (body) cells Produces two new cells identical to the parent cell
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Chromosomes
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Chromosomes Chromosomes store genetic information
Human cells have 46 chromosomes: 23 pairs
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Called Sister Chromatids
Chromosomes Duplicated chromosomes are called chromatids chromatids held together by centromere Called Sister Chromatids
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Body cells are diploid = 2n
The pairs are called homologs
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How can the cell divide and cut its chromosome number in ½?
The Problem: How can the cell divide and cut its chromosome number in ½? How can we go from 2n to 1n?
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Meiosis
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Facts About Meiosis Two divisions- Meiosis I and II
reduction- division Original cell is diploid (2n) Four daughter cells are haploid (1n)
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Facts About Meiosis Produces gametes (eggs & sperm)
Occurs in the testes in males (Spermatogenesis) Occurs in the ovaries in females (Oogenesis)
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How do you cut the chromosome number in ½?
Here is the problem: How do you cut the chromosome number in ½? How do you divide and get the right chromosomes into each cell?
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A major difference between the divisions of mitosis and meiosis:
The HOMOLOGS pair up before dividing
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Meiosis: Two Cell Divisions
Sister chromatids separate Meiosis I Meiosis II Homologs separate Diploid Diploid Haploid
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Prophase I Late prophase Early prophase Chromosomes condense.
Spindle forms. Nuclear envelope fragments. Early prophase Homologs pair. Crossing over occurs.
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Tetrads Form in Prophase I
Homologous chromosomes (each with sister chromatids) Join to form a TETRAD Called Synapsis
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Crossing-Over Homologous chromosomes in a tetrad cross over each other
Pieces of chromosomes or genes are exchanged Produces Genetic recombination in the offspring
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Crossing-Over Crossing-over multiplies the already huge number of different gamete types produced by independent assortment
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Homologous pairs of chromosomes align along the equator of the cell
Metaphase I Homologous pairs of chromosomes align along the equator of the cell
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Anaphase I Homologs separate and move to opposite poles.
Sister chromatids remain attached at their centromeres.
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Telophase I Nuclear envelopes reassemble. Spindle disappears.
Cytokinesis divides cell into two.
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Prophase II Nuclear envelope fragments. Spindle forms.
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Metaphase II Chromosomes align along equator of cell.
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Anaphase II Sister chromatids separate and move to opposite poles.
Equator Pole Sister chromatids separate and move to opposite poles.
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Telophase II Nuclear envelope assembles. Chromosomes decondense.
Spindle disappears. Cytokinesis divides cell into two.
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Results of Meiosis Gametes (egg & sperm) form
Four haploid cells with one copy of each chromosome One allele of each gene Different combinations of alleles for different genes along the chromosome
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Oogenesis or Spermatogenesis
Gametogenesis Oogenesis or Spermatogenesis
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Spermatogenesis Occurs in the testes
Two divisions produce 4 spermatids Spermatids mature into sperm Men produce about 250,000,000 sperm per day
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Spermatogenesis
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Oogenesis Occurs in the ovaries
Two divisions produce 3 polar bodies that die and 1 egg Polar bodies die because of unequal division of cytoplasm Immature egg called oocyte Starting at puberty, one oocyte matures into an ovum (egg) every 28 days
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Oogenesis Meiosis I Mitosis Mature egg Oogonium (diploid) Ovum (egg) a
X a X a X Meiosis I a A X Mitosis Mature egg Oogonium (diploid) A X A X Ovum (egg) A X
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Comparing Mitosis and Meiosis
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Mitosis Meiosis WHAT it is used for How many daughter cells Are the daughters identical to the parent? If the parent is diploid with 16 chromosomes, what will the daughter be? Does the DNA need to replicate before division? Does crossing over occur?
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Comparison of Divisions
Mitosis Meiosis Number of divisions Number of daughter cells Genetically identical? Chromosome # Where When Role
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Comparison of Divisions
Mitosis Meiosis Number of divisions 1 2 Number of daughter cells 4 Genetically identical? Yes No Chromosome # Same as parent Half of parent Where Somatic cells Germ cells When Throughout life At sexual maturity Role Growth and repair Sexual reproduction
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