1. The extent of the PET hypometabolism may be substantially larger than the electrical focus.55 The relationship between the area of hypometabolism and the extent of surgical resection needed for seizure control—particularly in extratemporal foci—has not been clearly defined.56 Planned ictal FDG-PET imaging of patients with frequent or continuous partial seizures may offer a unique opportunity to study the metabolic pattern of the brain during ictal events. This may be especially important in patients with extensive underlying structural brain abnormalities in whom both routine morphologic and interictal functional imaging may not sufficiently localize the epileptogenic tissue for surgical planning. Planned ictal PET imaging may be a useful and potentially superior approach to ictal SPECT for identifying the epileptic focus in a selected group of patients with continuous or frequent simple partial seizures.57 Ictal FDG-PET showing intense hypermetabolism in a hypothalamic hamartoma in a patient with gelastic seizures has been reported.58
Source: Newborn, Atlas of Pediatric EEG
Citation: Laoprasert P. Atlas of Pediatric EEG; 2011 Available at: Accessed: November 10, 2017
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