1. Predictors of Memory in Healthy Aging: Polyunsaturated Fatty Acid Balance and Fornix White Matter Integrity
Marta K. Zamroziewicz 1, 2, 3 ;Erick J. Paul 1, 2 ;Chris E. Zwilling 1, 2 ;Aron K. Barbey 1, 2, 3, 4, 5, 6, 7 ;
1 Decision Neuroscience Laboratory, University of Illinois Urbana-Champaign, Urbana, IL, USA. ; 2 Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, USA. ; 3 Neuroscience Program, University of Illinois Urbana-Champaign, Urbana, IL, USA. ; 4 Department of Psychology, University of Illinois Urbana-Champaign, Urbana, IL, USA. ; 5 Carle Neuroscience Institute, Carle Foundation Hospital, Urbana, IL, USA. ; 6 Department of Internal Medicine, University of Illinois Urbana-Champaign, Urbana, IL, USA. ; 7 Institute for Genomic Biology, University of Illinois Urbana-Champaign, Champaign, IL, USA ;
Figure 1. Proposed mediation model The primary requirement for mediation is a significant indirect mediation effect, defined as the effect of the independent variable nutrient biomarker pattern through the mediation fractional anisotropy in white matter regions on the dependent variable memory.
Aging and Disease,null,8(4), Doi: /AD