1. Tissue/Organ Engineering
What will be covered.
Types of cells
Scaffolds
Biocompatibility

2. 122,572 8,030 How can this be useful? Heart Disease
6,000,000
550,000
Pulmonary Disease (COPD)
12,000,000
Renal Failure
530,000
Heart – 0.6
Lung – 2.5
Kidney – 3.3
122,572
8,030

3. What is tissue engineering?

4. What kinds of cells are used?
Specialized cells
How do we obtain them?
Stem Cells: Embryonic Vs. Placental/Umbilical
Use the patient’s cells

5. What methods are used to create scaffolds?
Things to consider
Biocompatibility
Vascularization
Biodegradability
Decellularization
ECM
Allows for vascularization
Allows for optimal biocompatibility
A “natural” scaffold

6. Summary This is still a developing technology.
The best method of scaffolding is using the process of decellularization, but there are others.
Stem cells can also be used to allow cells to grow and specialize.

7. Works Cited
Meul. CoeurHumain. Digital image. Commons Wikimedia. N.p., 22 Jan Web. <
"Organ Matching Process." Organdonor.gov. N.p., n.d. Web. 26 Sept
"Tissue Engineering." Wikipedia. Wikimedia Foundation, n.d. Web. 26 Sept
"Decellularization." Wikipedia. Wikimedia Foundation, n.d. Web. 26 Sept
Baptista, Pedro M. “The Use of Whole Organ Decellularization for the Generation of a Vascularized Liver Organoid.” Hepatology 53.2 (2011): Print
"About Us." <
“The ABCs of Organ Engineering” Lab/Inside-the-Lab.htm
“Tissue Engneering: How to build a heart” heart
“Vacanti mouse” <