1. From: Transplantation of Human Embryonic Stem Cell-Derived Retinal Cells into the Subretinal Space of a Non-Human Primate
Trans. Vis. Sci. Tech ;6(3):4. doi: /tvst.6.3.4
Figure Legend:
Transplanted cells migrate into inner retinal cell layers and extend axonal projections into the optic nerve. (A) At 12 weeks postinjection, few GFP+ cells were observed in the inner nuclear layer (arrowhead) and GCL (arrow). (B) Immunostaining of the subretinal mass of nonintegrated cells revealed few Ki-67+ cells (arrow). (C) Axonal projections emanating from the transplanted cells extended along the inner plexiform layer, GCL, and NFL. GFP+ projections were noted entering at the optic nerve head (D, inset and D, arrow), and extending into the retrolaminar optic nerve (D-D”). ON, optic nerve.
Date of download: 11/11/2017
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