1. Daily Starter 4/18/16
Define mutation. Think of a famous mutant, describe them. Is the mutation beneficial or harmful?

2. Mutations

3. Explore:
You are baking a cake for your best friends birthday. What happens if you read the directions incorrectly and forget to add an ingredient? What if you add them in the wrong order? you read the directions in correctly and forget to add an ingredient???

4. Explain: Notes
A mutation is any change in the DNA that results in different traits
DNA is made of four bases:
A and T
C and G

5. Chromosomes and DNA

6. Do you see the mutation?
Mutation= Change in the organism’s DNA

7. We can think of this as the DNA directions being jumbled up.
Explain: Notes
Two Types:
Gene Mutation- change in the DNA bases
We can think of this as the DNA directions being jumbled up.
Original Direction: Open the dog food and pour it into the bowl.
Open the dog and pour it into the bowl.
Open the dog foot and pour it into the bowl
Open the dog food and pour it into

8. Explain: Notes Substitution: base is changed Insertion: base is added
Open the dog foot and pour it into the bowl.
ATCG  TCGC
Insertion: base is added
Open the dog food cactus and pour it into the bowl.
ATCG  TAGCT
Deletion: base removed
Open the dog and pour it into the bowl.
ATCG  TGC
Frame Shift: starts/stops copying in wrong place
Food and pour it into the bowl open the dog.
ATCG  AG

9. Explain: Notes Two Types: Gene Mutation- change in the DNA bases
Chromosome Mutation- number of chromosomes changed.
Deleted or added (23 21 or 24)

10. What type of mutation? Gene or chromosome?
Insertion, deletion, or substitution?

11. What type of mutation? Gene or chromosome?
Insertion, deletion, or substitution?

12. Ex: Sickle Cell Anemia

13. Ex: Sickle Cell Anemia Sickle Cell RBC Normal RBC
Caused by single amino acid change in hemoglobin
Sickle Cell
RBC
Normal RBC

14. What type of mutation? Gene or chromosome?
Insertion, deletion, or substitution?

15. Ex: Cancer
Cancer occurs when mutations cause cells to grow in an uncontrolled way

16. Famous Mutants

17. Not all mutations are harmful!

18. The cat ate the rat

22. Other Mutations

23. Hairy ears

24. Patau Syndrome

25. Cri du chat Syndrome (deletion)

26. Fragile X chromosome

27. GOOD or BAD? Beneficial: Help an animal survive
Extra chromosome in plants makes them stronger and live longer
Harmful:
Hurt an organism
White alligators can not blend in with surround and they are unable to hunt or hide from predators.