1. Increased risk of bladder cancer with pioglitazone therapy in patients with diabetes: A meta-analysis 
Zhaowei Zhu, Zhoujun Shen, Yingli Lu, Shan Zhong, Chen Xu 
Diabetes Research and Clinical Practice 
Volume 98, Issue 1, Pages (October 2012)
DOI: /j.diabres
Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions

2. Fig. 1 Flowchart of study selection process.
Diabetes Research and Clinical Practice  , DOI: ( /j.diabres )
Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions

3. Fig. 2
Pooled estimate of relative risk and 95% CIs of bladder cancer associated with pioglitazone therapy based on five studies comprising 2,350,908 diabetic patients. Squares indicate relative risk in each study. The square size is proportional to the weight of the corresponding study in the meta-analysis; the length of horizontal lines represents the 95% CI. The unshaded diamond indicates the pooled relative risk and 95% CI.
Diabetes Research and Clinical Practice  , DOI: ( /j.diabres )
Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions

4. Fig. 3
Funnel plot of effect estimates for bladder cancer. Begg test, P= rr=relative risk; se=standard error.
Diabetes Research and Clinical Practice  , DOI: ( /j.diabres )
Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions