1. 3.1.1 – Sickle Cell Anemia

2. Terms to Know Component: Function: Plasma
Fluid that is composed of about 92% water, 7% vital proteins such as albumin, gamma globulin, anti- hemophilic factor, and other clotting factors, and 1% mineral salts, sugars, fats, hormones and vitamins. It is also the vehicle by which blood cells are carried around the body.
Red Blood Cells (Erythrocytes)
Cells that carry oxygen from the lungs to your body’s tissue and take carbon dioxide back to your lungs to be exhaled.
White Blood Cells (Leukocytes)
Cells that travel throughout the body and destroy bacteria, some produce antibodies against bacteria and viruses, and others help fight malignant diseases.
Platelets (Thrombocytes)
Small, colorless cell fragments in the blood whose main function is to interact with clotting proteins to stop or prevent bleeding.

3. Normal Blood

4. Sickle Cell Slide

5. Anemia Healthy red blood cells live for 90-120 days
When needed your body releases the hormone erythropietin in your kidneys to tell bone marrow to make more RBC
People with sickle cell have red blood cells that do not live as long as norm
As a result they become anemic – have a low RBC count
Anemia is diagnosed through a hematocrit test
Measures the volume of RBC compared to the whole volume of blood cells

6. Hematocrit Test Low Hematocrit (%) Normal Hematocrit High Hematocrit
Male
Female
<42
<35
42-54
35-46
>54
>46