1. Date of download: 11/12/2017
Copyright © ASME. All rights reserved.
Evaluating the Effect of Sinex® (0.05% Oxymetazoline) Nasal Spray on Reduction of Nasal Congestion Using Computational Fluid Dynamics
J Biomech Eng. 2015;137(8): doi: /
Figure Legend:
Nasal passages (darker gray region) reconstructed from MRI slices using Simpleware. Face included for illustrative purposes only.

2. Date of download: 11/12/2017
Copyright © ASME. All rights reserved.
Evaluating the Effect of Sinex® (0.05% Oxymetazoline) Nasal Spray on Reduction of Nasal Congestion Using Computational Fluid Dynamics
J Biomech Eng. 2015;137(8): doi: /
Figure Legend:
Calculation of nasal resistance; steeper slopes indicate higher nasal resistance

3. Date of download: 11/12/2017
Copyright © ASME. All rights reserved.
Evaluating the Effect of Sinex® (0.05% Oxymetazoline) Nasal Spray on Reduction of Nasal Congestion Using Computational Fluid Dynamics
J Biomech Eng. 2015;137(8): doi: /
Figure Legend:
3D CAD models reconstructed from MRI slices of subject NN (Sinex®) at the three time points qualitatively show an increase in flow volume after treatment

4. Date of download: 11/12/2017
Copyright © ASME. All rights reserved.
Evaluating the Effect of Sinex® (0.05% Oxymetazoline) Nasal Spray on Reduction of Nasal Congestion Using Computational Fluid Dynamics
J Biomech Eng. 2015;137(8): doi: /
Figure Legend:
Flow path lines in nasal passages of subject NN (Sinex®) at three time points: (a) predose, (b) 8 hr post-treatment, and (c) 12 hr post-treatment. Dashed box showing location of nasal valve in predose image.

5. Date of download: 11/12/2017
Copyright © ASME. All rights reserved.
Evaluating the Effect of Sinex® (0.05% Oxymetazoline) Nasal Spray on Reduction of Nasal Congestion Using Computational Fluid Dynamics
J Biomech Eng. 2015;137(8): doi: /
Figure Legend:
Nasal passage anatomy (coronal view) SM: superior meatus; MM: medial meatus; IM: inferior meatus

6. Date of download: 11/12/2017
Copyright © ASME. All rights reserved.
Evaluating the Effect of Sinex® (0.05% Oxymetazoline) Nasal Spray on Reduction of Nasal Congestion Using Computational Fluid Dynamics
J Biomech Eng. 2015;137(8): doi: /
Figure Legend:
Scatter plots for percentage reduction of nasal resistance: (a) after 8 hr; (b) after 12 hr

7. Date of download: 11/12/2017
Copyright © ASME. All rights reserved.
Evaluating the Effect of Sinex® (0.05% Oxymetazoline) Nasal Spray on Reduction of Nasal Congestion Using Computational Fluid Dynamics
J Biomech Eng. 2015;137(8): doi: /
Figure Legend:
Chart of Relative Risk (RR) reductions of 50% or more at both time points