1. Glycolysis

2. GLYCOLYTIC PATHWAY

3. Glucose metabolism in cells
Glycolysis: 1.) Phosphorylation of glucose to form glucose-6-phosphate by enzyme HEXOKINASE, GLUCOKINASE. Hexokinase Glucose glucose-6-p + ADP ATP Glucokinase

4. ISOMERASE 2. ) Glucose -6- p fructose -6- p PHOSPHOFRUCTOKINASE 3
ISOMERASE 2.) Glucose -6- p fructose -6- p PHOSPHOFRUCTOKINASE 3.) Fructose-6-p fructose-1,6-biphosphate ATP

5. 4.) fructose-1,6-biphosphate dihydroxyacetone phosphate
ALDOLASE
4.) fructose-1,6-biphosphate dihydroxyacetone phosphate +
glyceraldehyde-3-p
(interchangable compound)

6. PHOSPHATE DEHYDROGENASE
glyceraldehyde-3-p ,3-biphosphoglycerate
NAD NADH
PHOSPHOGLYCERATE KINASE
6. 1,3-biphosphoglycerate phosphoglycerate
ADP ATP

7. 7.) 3-phosphoglycerate 2-phosphoglycerate
MUTASE
7.) 3-phosphoglycerate phosphoglycerate
ENOLASE
8.) 2-phosphoglycerate phosphoenol pyrovate
PYRUVATE KINASE
9.) Phosphoenol pyruvate pyruvate
ADP ATP

8. OUTCOME OF GLYCOLYSIS:
Loss of 2 ATP molecules at the beginning
gain of 2 NADH and 6 ATP
formation of 2 ATP in the final step *2
FINAL GAIN = 8 ATP