1. PROJECT:
Model DNA

2. Can you see the DNA? Can you touch it?

3. HOOK

4. IBE
Is the DNA the same in all organisms?

5. J-TPS (Justify –Think Pair Share)

6. DNA structure is the same in all organisms

7. DNA is composed of nucleotides
DNA is made up of a polymer (long chain) of nucleotides.
Each nucleotide has three parts.
A phosphate group
A deoxyribose sugar
A nitrogen-containing base

8. The Nucleotide Bases
The nitrogen containing bases are the only parts in the nucleotides that are different.

9. White board
DNA structure is the same in all organisms
A. True
B False

10. Watson and Crick determined the three-dimensional structure of DNA by building models
These scientists discovered that the DNA molecule is a double helix that is made up of a sugar-phosphate backbone on the outside with bases on the inside.

11. Watson and Crick’s discovery was built on the work of Rosalind Franklin and Erwin Chargaff.
Franklin’s x-ray images suggested that DNA was a double helix of even width.
Chargaff’s rules stated that A=T and C=G.

12. Nucleotides always pair in the same way
The base-pairing rules show how nucleotides always pair up in DNA.
A pairs with T
C pairs with G C G T A

13. The backbone is connected by covalent bonds.
The bases are connected by hydrogen bonds.
hydrogen bond
covalent bond

14. G A T T A C A Practice DNA Base Pairs
“Gattaca” is a science fiction movie starring Uma Thurman, Ethan Hawke, and Jude Law

15. G A T T A C A C T A A T G T Practice DNA Base Pairs
“Gattaca” is a science fiction movie starring Uma Thurman, Ethan Hawke, and Jude Law

16. DNA vs. RNA DNA RNA Sugar = deoxyribose Sugar = ribose
Double-stranded molecule
Single-stranded molecule
Thymine bonds with adenine
Uracil instead of thymine

17. White board The following sequence belongs to AAUCGCGUAACCGGCC A. DNA
B. RNA
C. DNA & RNA
D Not enough information is provided

18. White board
What’s wrong in this sequence?
AATCGCGUAACCGGCC

19. DNA is like a fingerprint because everyone’s is a little different!
Revisit IBE
DNA is like a fingerprint because everyone’s is a little different!
You can tell people apart by their fingerprints………
and their DNA!
How would the police look at DNA to figure out who committed a crime?

20. SWBAT explain how DNA replicates
DNA replication
Unit 5
LT b
SWBAT explain how DNA replicates

22. IBE
In order for Peter Parker to become “Spiderman” what does it need to happen?

23. J-TPS (Justify –Think Pair Share)

24. DNA replication copies the genetic information of a cell.

25. During what stage of cell cycle does DNA get replicated?

26. During what stage of cell cycle does DNA get replicated?

27. DNA replication – helix unzips

28. DNA replication – two strands are separated

29. DNA replication – each side is now a template

30. DNA replication – two identical strands of DNA
Original DNA strands

31. DNA replication
Newly assembled DNA strands

32. DNA replication
Semi-conservative replication

33. White board question DNA replication is
A. the process of making proteins
B. the process of making RNA
C. the process of making new organelles
D. the process of copying DNA

34. Proteins carry out the process of replication.
nucleotide
The DNA molecule unzips in both directions.

35. DNA Polymerase
DNA polymerase brings nucleotides together to form the new DNA strand
DNA polymerase
new strand
nucleotide

36. Semiconservative model of DNA
The process of making new DNA molecules is semiconservative; one original and one new strand of DNA
original strand
new strand
Two molecules of DNA

37. Leading strand synthesis continues in a 5’ to 3’ direction.
Replication 5’ 3’
Overall direction
of replication
Leading strand synthesis continues in a
5’ to 3’ direction.

38. White board
“The process of making new DNA molecules is semiconservative” What does it mean?

39. IBE
In order for Peter Parker to become “Spiderman” what does it need to happen?

40. DNA replication video