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Inflammatory Cytokines in the BAL of Patients With ARDS

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Presentation on theme: "Inflammatory Cytokines in the BAL of Patients With ARDS"— Presentation transcript:

1 Inflammatory Cytokines in the BAL of Patients With ARDS
G. Umberto Meduri, MD, FCCP, Gary Kohler, MD, Stacey Headley, MD, Elizabeth Tolley, PhD, Frankie Stentz, PhD, Arnold Postlethwaite, MD  CHEST  Volume 108, Issue 5, Pages (November 1995) DOI: /chest Copyright © 1995 The American College of Chest Physicians Terms and Conditions

2 FIGURE 1 Kaplan-Meier survival curve over time.
CHEST  , DOI: ( /chest ) Copyright © 1995 The American College of Chest Physicians Terms and Conditions

3 FIGURE 2 LIS in survivors (closed triangles) and nonsurvivors (open circles) during the first week of ARDS. CHEST  , DOI: ( /chest ) Copyright © 1995 The American College of Chest Physicians Terms and Conditions

4 FIGURE 3 Mean (±SE) BAL albumin and TP levels in survivors and nonsurvivors over time. In nonsurvivors of ARDS (gray bar), mean BAL albumin and TP levels (g/L) remained elevated over time. BAL albumin levels over time were 447±31, 404±54, and 337±61. BAL TP levels over time were 957±53, 788±94, and 695±108. In survivors of ARDS (white bar), mean BAL albumin and TP levels (g/L) rapidly decreased over time. BAL albumin levels over time were 406± 13, 124±27. BAL TP levels over time were 874 ±28 and CHEST  , DOI: ( /chest ) Copyright © 1995 The American College of Chest Physicians Terms and Conditions

5 FIGURE 4 Relationships among BAL TNF-α, IL-1ß, IL-6, and IL-8 and BAL albumin and TP. CHEST  , DOI: ( /chest ) Copyright © 1995 The American College of Chest Physicians Terms and Conditions


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