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Human Herpesvirus 6 Reactivation in Drug-induced Hypersensitivity Syndrome and DRESS Validation Score  Yukiko Ushigome, MD, Yoko Kano, MD, Kazuhisa Hirahara,

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Presentation on theme: "Human Herpesvirus 6 Reactivation in Drug-induced Hypersensitivity Syndrome and DRESS Validation Score  Yukiko Ushigome, MD, Yoko Kano, MD, Kazuhisa Hirahara,"— Presentation transcript:

1 Human Herpesvirus 6 Reactivation in Drug-induced Hypersensitivity Syndrome and DRESS Validation Score  Yukiko Ushigome, MD, Yoko Kano, MD, Kazuhisa Hirahara, MD, Tetsuo Shiohara, MD  The American Journal of Medicine  Volume 125, Issue 7, Pages e9-e10 (July 2012) DOI: /j.amjmed Copyright © 2012 Elsevier Inc. Terms and Conditions

2 Figure 1 Association between human herpesvirus 6 (HHV-6) DNA loads and cytomegalovirus reactivation in drug-induced hypersensitivity syndrome and drug reaction with eosinophilia and systemic symptoms (DRESS) validation score. HHV-6 DNA and cytomegalovirus DNA in 106 leukocytes were measured by using real-time polymerase chain reaction assay. Final score 4-5=probable case; final score>5=definite case. •=HHV-6 DNA and cytomegalovirus DNA were detected; ○=HHV-6 DNA alone was detected; *=the second time evaluation of cytomegalovirus DNA was not carried out because of sudden death. The American Journal of Medicine  , e9-e10DOI: ( /j.amjmed ) Copyright © 2012 Elsevier Inc. Terms and Conditions


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