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Published byDorothy Preston Modified over 6 years ago
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Basic elements of renal-body fluid feedback mechanism for long-term regulation of blood pressure. A key component of this feedback is the effect of arterial pressure on urine sodium excretion, called pressure natriuresis/diuresis. The red dashed lines show altered pressure natriuresis in salt-sensitive and salt-resistant hypertension. Increased arterial pressure may cause secondary increases in total peripheral resistance via pressure-dependent or flow-dependent “autoregulation” in various tissues. Increased vascular capacity tends to reduce mean circulatory filling pressure. Source: PATHOPHYSIOLOGY OF HYPERTENSION, Hurst's The Heart, 14e Citation: Fuster V, Harrington RA, Narula J, Eapen ZJ. Hurst's The Heart, 14e; 2017 Available at: Accessed: November 14, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved
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