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Neuro-ophthalmology
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Broadman area 17
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Lesions in Visual Pathway
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SIGNS OF OPTIC NERVE DYSFUNCTION:
1- Decreased visual acuity. 2- Diminish light pupillary reflex. 3- Dyschromatopsia 4- Diminished light brightness sensitivity. 5- Visual field defect
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SPECIAL INVESTIGATIONS:
perimetry Visual Evoked Potential (VEP) MRI Fluorescein angiography
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OPTIC NEURITIS 1- Ophthalmoscopic classification:
a- Retrobulbar neuritis b- Papillitis
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OPTIC NEURITIS 2- Aetiological classification:
a- Demyelinating:most common cause. b- Para-infectious: a viral or immunization. c- Infectious: d- Autoimmune: systemic autoimmune disease.
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OPTIC ATROPHY PRIMARY
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OPTIC ATROPHY 1- Primary optic atrophy Causes:
- Retrobulbar neuritis (not papillitis). - Compressive lesions. - Hereditary optic neuropathies. - Toxic and nutritional optic neuropathies.
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OPTIC ATROPHY SECONDARY
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OPTIC ATROPHY 2- Secondary optic atrophy Causes:
- Chronic papilloedema. - AION (Anterior Ischaemic Optic Neuropathy): - Papillitis.
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PAPILLOEDEMA BILATERAL
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Differential diagnosis of papilloedema:
1- Malignant hypertension. 2- Bilateral papillitis. 3- Bilateral compressive thyroid ophthalmopathy. 4- Bilateral simultaneous AION. 5- Bilateral compromised venous drainage.
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ABNORMAL PUPILLARY REACTION
Applied Anatomy
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AFFERENT PUPILLARY CONDUCTION DEFECTS
A total afferent defect (TAPD, amaurotic pupil) A relative afferent defect (RAPD, Marcus Gunn pupil)
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RAPD
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NEAR REFLEX 'light-near dissociation' Dark Light Near
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SYMPATHETIC SUPPLY Applied Anatomy
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HORNER SYNDROM
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