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Methods to Identify and Access Trials in Iowa

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1 Methods to Identify and Access Trials in Iowa
Kathleen Ollinger, BSN, RN, OCN Lead Clinical Trial Nurse Mercy Cancer Center – Des Moines

2 Iowa Cancer Plan Goal 12: Increase awareness of and participation in cancer research including clinical trials focused on cancer prevention, early detection and treatment. Actions: a. Support all phases of cancer research across the state including laboratory research, clinical trials and population research. b. Expand reach of community oncology practices clinical research programs through increasing the reach of NCI clinical trial networks. c. Link clinical research efforts of Iowa’s NCI-designated Holden Comprehensive Cancer Center at the University of Iowa with collaborating practices throughout the state for access to emerging treatment and interventions offered through clinical trials. d. Develop and disseminate education campaigns to inform the public about research, including clinical trials. e. Create a statewide clinical trials database. f. Increase accessibility of cancer clinical trials to all cancer patients. g. Support policies and systems changes that expand access to and use of cancer clinical trials. h. Build or sustain coalitions with key stakeholders to enhance support for cancer research and the availability of cancer clinical trials. i. Increase collaboration between researchers to better translate research findings into practice.

3 Clinicaltrials.gov

4 Advanced Search in Clincialtrials.gov

5 American Cancer Society

6 Cancer Center Websites

7 NCI’s National Clinical Trials Network (NCTN)

8 Structure of NCTN National Cancer Institute, 2015
Healthcare organizations can belong to more than one group, and membership in at least one group allows a site to participate in the trials led by any NCTN group for which their investigators are qualified. National Cancer Institute, 2015

9 National Cancer Institute, 2015

10 Iowa Cancer Plan Goal 12: Increase awareness of and participation in cancer research including clinical trials focused on cancer prevention, early detection and treatment. Actions: a. Support all phases of cancer research across the state including laboratory research, clinical trials and population research. b. Expand reach of community oncology practices clinical research programs through increasing the reach of NCI clinical trial networks. c. Link clinical research efforts of Iowa’s NCI-designated Holden Comprehensive Cancer Center at the University of Iowa with collaborating practices throughout the state for access to emerging treatment and interventions offered through clinical trials. d. Develop and disseminate education campaigns to inform the public about research, including clinical trials. e. Create a statewide clinical trials database. f. Increase accessibility of cancer clinical trials to all cancer patients. g. Support policies and systems changes that expand access to and use of cancer clinical trials. h. Build or sustain coalitions with key stakeholders to enhance support for cancer research and the availability of cancer clinical trials. i. Increase collaboration between researchers to better translate research findings into practice.

11 January 19, 2005 Clinical Trial Access and Networks
Carlie Etscheidt RN, MSN, CCRP Asst. Director – Clinical Research Services UIHC - Holden Comprehensive Cancer Center

12 Types of Trials Available
National Clinical Trials Network (NCTN) Consortium Industry Sponsored Investigator Initiated Early Phase Trials AYA (Adolescent and Young Adult (13-31)

13 Trial Focus Diagnostic Prevention Supportive Care Treatment

14 Industry Sponsored Number of Industry Sponsors Growing
Long Established Novartis Merck New Companies New Link Genetics (Ames based)

15 Consortium Big Ten Cancer Research Consortium (BTCRC)
Hoosier Oncology Group (HOG) Sarcoma Alliance for Research through Collaboration (SARC)

16 Investigator Initiated
Local investigator develop and write their own studies Support available from a variety of sources Industry Grant ACS

17 NCTN Alliance for Clinical Trials in Oncology NRG Oncology SWOG
ECOG-ACRIN COG (Children’s Oncology Group)

18 Flow Chart How to Find Open Trials – Holden Comprehensive Cancer Center website  Learn about our Research  Clinical Research  OnCore: Searchable Clinical Trials Database HCCC Flowchart


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