1. Behavioral dysfunction is observed in immunodeficient mice.
Behavioral dysfunction is observed in immunodeficient mice. A: nonspatial memory was assessed in wild-type (WT) C57BL/6 and Rag1−/− mice by the novel object test, with or without exposure to water avoidance stress (WAS), with memory determined as the exploration ratio. B and C: anxiety-like behavior was studied in the same groups of mice by using a light/dark box, with anxiety determined as total time spent in the light (B) and exploratory behavior determined as the frequency of transitions between the light and dark compartments (C). Means ± SE; **P < 0.01; 1-way ANOVA, Newman-Keuls post hoc; N = 6–8 mice/group.
Carli J. Smith et al. Am J Physiol Gastrointest Liver Physiol 2014;307:G793-G802
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