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Comparison of Outcomes Twelve Years After Antireflux Surgery or Omeprazole Maintenance Therapy for Reflux Esophagitis  Lars Lundell, Pekka Miettinen,

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Presentation on theme: "Comparison of Outcomes Twelve Years After Antireflux Surgery or Omeprazole Maintenance Therapy for Reflux Esophagitis  Lars Lundell, Pekka Miettinen,"— Presentation transcript:

1 Comparison of Outcomes Twelve Years After Antireflux Surgery or Omeprazole Maintenance Therapy for Reflux Esophagitis  Lars Lundell, Pekka Miettinen, Helge E. Myrvold, Jan G. Hatlebakk, Lene Wallin, Cecilia Engström, Risto Julkunen, Madeline Montgomery, Anders Malm, Tore Lind, Anders Walan  Clinical Gastroenterology and Hepatology  Volume 7, Issue 12, Pages (December 2009) DOI: /j.cgh Copyright © 2009 AGA Institute Terms and Conditions

2 Figure 1 Proportions of patients in sustained remission (A- and B-analyses). In the A-analysis, treatment failure was defined as first occurrence of endoscopic esophagitis or symptomatic relapse, or the need to change therapy. In the B-analysis, allowance was made for dose adjustment of OME after the first recurrence. Clinical Gastroenterology and Hepatology 2009 7, DOI: ( /j.cgh ) Copyright © 2009 AGA Institute Terms and Conditions

3 Figure 2 Proportions of patients with (A) heartburn, (B) acid regurgitation, (C) any dysphagia, or (D) rectal flatulence after ARS or medical therapy. Clinical Gastroenterology and Hepatology 2009 7, DOI: ( /j.cgh ) Copyright © 2009 AGA Institute Terms and Conditions

4 Figure 3 (A) Box plots of GSRS total score (1.7 is considered to represent a normal value as captured from a healthy control population). In (B) a corresponding box plot of PGWB total score (normal value, 102) is depicted.3,15,16 Clinical Gastroenterology and Hepatology 2009 7, DOI: ( /j.cgh ) Copyright © 2009 AGA Institute Terms and Conditions


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