1. Acute Kidney Injury: An Introduction
Hussein Sheashaa, MD, FACP
Professor of Nephrology, Urology and Nephrology Center and Director of Medical E-Learning Unit, Mansoura University, and Executive Director of ESNT- Virtual Academy:

2. Mortality in AKI
Am J Med 2005;118:827–832.

3. Mortality in AKI Kidney International advance online publication
, 1 May 2013; in Press

5. RIFLE

6. AKIN

7. AKI-KDIGO Guidelines
2.1.1: AKI is defined as any of the following (Not Graded):
Increase in SCr by 0.3 mg/dL (26.5 mol/L) within 48 hours; or
Increase in SCr to 1.5 times baseline, which is known or presumed to have occurred within the prior 7 days; or
Urine volume 0.5 mL/kg/h for 6 hours.
Kidney Int Suppl. 2012;2:1-138.

8. AKIN and Mortality in Critically Ill Patients ( n= 1625 patients)
Based on serum Cr
Based on Urine output
Nephrol Dial Transplant (2012) 27: 161–165

9. 32,045 adult
ICU patients
J Am Soc Nephrol 2015;

10. Comprehensive textbook of Nephrology 2010
Presentation
History and manifestations of the cause
Oliguria or non-oliguria
Edema, hypertension
Uremic symptoms
Manifestations of complications.
Comprehensive textbook of Nephrology 2010

11. Symptoms Possible Diagnosis
Presentation
Symptoms Possible Diagnosis

12. Acute Kidney Injury: Role of Ultrasound
Clin J Am Soc Nephrol 9: 382–394, Feb 2014.

13. Am J Kidney Dis. June 2014;63(6):

14. Clin J Am Soc Nephrol 9: 1132–1137, June 2014

15. AKI KDIGO Guidelines: Do not use
Low dose dopamine (1A)
Fenoldopam (1C)
ANP (1C- IB)
Rh-IGF-1 (IB)
Nephrol Dial Transplant (2012) 0: 1–10

16. Clin J Am Soc Nephrol 10: 21–28, 2015

18. Cardiorenal Syndrome

20. Example from a 1915 Death Certificate from Massachusetts
Example from a 1915 Death Certificate from Massachusetts. From Rudy’s List of Archaic Medical Terms at ttp:// Stroke.htm

21. Dialytic Support

24. “You can't prevent what you can't predict.” K.M. Mac Aulay