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Le Peng, Xin Zhang, De-ying Kang, Xue-ting Liu, Qi Hong 

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1 Effectiveness and safety of Wuling capsule for post stroke depression: A systematic review 
Le Peng, Xin Zhang, De-ying Kang, Xue-ting Liu, Qi Hong  Complementary Therapies in Medicine  Volume 22, Issue 3, Pages (June 2014) DOI: /j.ctim Copyright © 2014 The Authors Terms and Conditions

2 Figure 1 Flow diagram of the selection process. Abbreviations: CENTRAL, Cochrane Central Register of Controlled Trials; CBM, Chinese Biomedicine Database; CNKI, China National Knowledge Infrastructure; VIP, Chinese Scientific Journals Database; CJP, Chinese Journal of Psychiatry; CJNMD, Chinese Journal of Nervous and Mental Diseases; WJITWM, World Journal of Integrated Traditional and Western Medicine; CJIM, Chinese Journal of Integrative Medicine; JCIM, Journal of Chinese Integrative Medicine; JTCM, Journal of Traditional Chinese Medicine; JBUTCM, Journal of Beijing University of Traditional Chinese Medicine. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions

3 Figure 2 Meta-analysis of treatment effect of Wuling capsule vs. No treatment on HAMD scores changes. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions

4 Figure 3 Meta-analysis of treatment effect of Wuling capsule plus Deanxit vs. Deanxit on HAMD scores changes. Annotation: Combination=Wuling capsule plus Deanxit. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions

5 Figure 4 Meta-analysis of treatment effect of Wuling capsule plus Fluoxetine vs. Fluoxetine on HAMD scores changes. Annotation: Combination=Wuling capsule plus Fluoxetine. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions

6 Figure 5 Meta-analysis of treatment effect of Wuling capsule plus Sertraline vs. Sertraline on HAMD scores changes. Annotation: Combination=Wuling capsule plus Sertraline. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions

7 Figure 6 Meta-analysis of treatment effect of Wuling capsule plus Paroxetine vs. Paroxetine on HAMD scores changes. Annotation: Combination=Wuling capsule plus Paroxetine. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions

8 Figure 7 Meta-analysis of treatment effect of Wuling capsule plus Citalopram vs. Citalopram on HAMD scores changes. Annotation: Combination=Wuling capsule plus Citalopram. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions

9 Figure 8 Meta-analysis of treatment effect of Wuling capsule vs. No treatment on response rate. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions

10 Figure 9 Meta-analysis of treatment effect of Wuling capsule plus Deanxit vs. Deanxit on response rate. Annotation: Combination=Wuling capsule plus Deanxit. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions

11 Figure 10 Meta-analysis of treatment effect of Wuling capsule plus Fluoxetine vs. Fluoxetine on response rate. Annotation: Combination=Wuling capsule plus Fluoxetine. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions

12 Figure 11 Meta-analysis of treatment effect of Wuling capsule plus Sertraline vs. Sertraline on response rate. Annotation: Combination=Wuling capsule plus Sertraline. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions

13 Figure 12 Meta-analysis of treatment effect of Wuling capsule plus Paroxetine vs. Paroxetine on response rate. Annotation: Combination=Wuling capsule plus Paroxetine. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions

14 Figure 13 Meta-analysis of treatment effect of Wuling capsule plus Citalopram vs. Citalopram on response rate. Annotation: Combination=Wuling capsule plus Citalopram. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions

15 Figure 14 Meta-analysis of treatment effect of Wuling capsule plus antidepressants vs. antidepressants on response rate. Annotation: Combination=Wuling capsule plus antidepressants; antidepressants=Deanxit, Fluoxetine, Sertraline, Paroxetine or Citalopram. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions

16 Figure 15 Funnel plot. Annotation: Comparison=Wuling capsule plus antidepressants vs. antidepressants; outcome=response rate; antidepressants=Deanxit, Fluoxetine, Sertraline, Paroxetine or Citalopram. Complementary Therapies in Medicine  , DOI: ( /j.ctim ) Copyright © 2014 The Authors Terms and Conditions


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