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Volume 135, Issue 1, Pages (January 2009)

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Presentation on theme: "Volume 135, Issue 1, Pages (January 2009)"— Presentation transcript:

1 Volume 135, Issue 1, Pages 225-227 (January 2009)
A 22-Year-Old Man With Headache and Stiff Neck After a Water Skiing Fall  Kristie Jones, MD, Ekachai Singhatiraj, MD, Rebecca MacDougall, MD, Thomas R. Beaver, MD, Kenneth Nugent, MD, FCCP  CHEST  Volume 135, Issue 1, Pages (January 2009) DOI: /chest Copyright © 2009 The American College of Chest Physicians Terms and Conditions

2 Figure 1 Wright-Giemsa-stained cytospin of CSF (original × 400) reveals copious neutrophils (white arrow), lymphocytes (small arrow), and occasional amoeboid structures (large arrow). Note the numerous cytoplasmic vacuoles, pale staining nuclei (asterisk) with prominent karyosome. CHEST  , DOI: ( /chest ) Copyright © 2009 The American College of Chest Physicians Terms and Conditions

3 Figure 2 Top left, A: Periventricular white matter (hematoxylin-eosin, original × 100). Top right, B: Higher power (original × 1,000) showing amoeba [arrows] associated with edema as well as neuropil destruction. The trophozoite is 20 to 30 microns in size with a large nucleus and a centrally placed karyosome and surrounding halo. Bottom left, C: Brain tissue with positive immunofluorescent staining for anti-N fowleri serum (original × 100). Bottom right, D: Higher power (original × 1,000) showing strongly positive immunofluorescent staining with N fowleri antiserum. CHEST  , DOI: ( /chest ) Copyright © 2009 The American College of Chest Physicians Terms and Conditions


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