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Mouse Exercise Monitoring System
Erik Lappinen, Brooks Alford, Elizabeth Smith, Matt Gallegly Advisors: Dr. Michael McDonald, Dr. Randall Reiserer Vanderbilt University Department of Biomedical Engineering
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Objectives Project Description Background Requirements Hardware
Software Timeline Budget
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Project Description Large scale monitoring system for mice involved in pharmacological studies Display and record data from exercise wheel motion Possible to monitor up to 100 cages simultaneously
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Project Background Exercise wheels provide wealth of information about mouse behavior and physiological changes Mouse testing accounts for 85-90% of all testing done in pharmaceuticals $400,000,000 development cost per drug in the U.S.
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Project Requirements Required: Wish List: Monitor speed and distance
Identify individual mice Real-time Store data for future analysis “Mouse Proof” Wish List: Monitor directionality of exercise wheel Addition of visual graphs of velocity and distance
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Hardware Matched IR LED light source/photosensor pair
Reflective surface placed on small portion of back side of mouse wheel surface
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Signal from Sensors Response for forward motion
Response for reverse motion Sensor 2
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Software Build off of existing LabView VI
Continuously retrieves data from one or more analog input channels using an external scan clock
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Timeline March 1 – All software completed with ten working units ready for testing Thru March - Complete testing April 1 - Project completed
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Budget TOTAL: ~ $1900 IR LED's: 100 @ $0.37 IR Detectors: 200 @ $0.28
CPU: $936.00 Digital I/O Cards: $145, $391.50 Connector block/cable kit: $63 Supplies for chassis (wood): ~$250 Wires, cables, etc: ~$100 Texts: $70 TOTAL: ~ $1900
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