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Case presented by Dr Schwartz

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1 Case presented by Dr Schwartz
77 yo man: PMH – multiple medical problems 2003: L hemicolectomy stage III colon CA  6 mos adjuvant 5-FU/LV 8/2007: orchiectomy for DLBCL  R-CVP x 8 (h/o valvular heart ds), persistent tx-induced neuropathy 8/2009: NED 2010: abdominal pain  CEA >1200  PET/CT = liver lesions and 6.8 cm RP mass (? etiology) Biopsy x 2 = met colon CA

2 Case continued: 10/2010: FOLFIRI but enteritis and GI bleed post cycle 2 despite dose reduction 11/2010: Kras status identified from liver bx = wt Irinotecan/cetuximab with manageable rash and diarrhea CEA falling  rescan pending

3 Case presented by Dr Schwartz
77 yo man: PMH – multiple medical problems 2003: L hemicolectomy stage III colon CA  6 mos adjuvant 5-FU/LV 8/2007: orchiectomy for DLBCL  R-CVP x 8 (h/o valvular heart ds), persistent tx-induced neuropathy 8/2009: NED 2010: abdominal pain  CEA >1200  PET/CT = liver lesions and 6.8 cm RP mass (? etiology) Biopsy x 2 = met colon CA

4 Case continued: 10/2010: FOLFIRI but enteritis and GI bleed post cycle 2 despite dose reduction 11/2010: Kras status identified from liver bx = wt Irinotecan/cetuximab with manageable rash and diarrhea CEA falling  rescan pending

5 Case presented by Dr Schwartz
77 yo man: PMH – multiple medical problems 2003: L hemicolectomy stage III colon CA  6 mos adjuvant 5-FU/LV 8/2007: orchiectomy for DLBCL  R-CVP x 8 (h/o valvular heart ds), persistent tx-induced neuropathy 8/2009: NED 2010: abdominal pain  CEA >1200  PET/CT = liver lesions and 6.8 cm RP mass (? etiology) Biopsy x 2 = met colon CA

6 Case continued: 10/2010: FOLFIRI but enteritis and GI bleed post cycle 2 despite dose reduction 11/2010: Kras status identified from liver bx = wt Irinotecan/cetuximab with manageable rash and diarrhea CEA falling  rescan pending

7 National GI Tumor Board Clinical Investigators Provide Their Perspectives on Current Cases of Gastrointestinal Cancer Friday, January 21, :00 PM – 9:30 PM San Francisco, California Moderator Neil Love, MD Faculty Charles D Blanke, MD David Cunningham, MD Steven A Curley, MD Eileen M O’Reilly, MD Eric Van Cutsem, MD, PhD Andrew X Zhu, MD, PhD 7 7


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