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Volume 157, Issue 1, Pages (July 2001)

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Presentation on theme: "Volume 157, Issue 1, Pages (July 2001)"— Presentation transcript:

1 Volume 157, Issue 1, Pages 13-21 (July 2001)
Effects of the heparin-mimicking compound RG on lipoprotein lipase and on lipase mediated binding of LDL to cells  Lucyna Neuger, Toralph Ruge, Elena Makoveichuk, Israel Vlodavsky, Gunilla Olivecrona  Atherosclerosis  Volume 157, Issue 1, Pages (July 2001) DOI: /S (00)

2 Fig. 5 Effects of heparin or RG on lipoprotein lipase (LPL) mediated binding and uptake of [125I]LDL by THP-I monocyte-derived macrophages. Cells were incubated for 2 h at 4°C (upper panel) or 37°C (lower panel) in medium containing 5 μg [125I]LDL/ml, 10 μg LPL/ml and different concentrations of heparin (filled bars) or RG (hatched bars). Binding and uptake of LDL was determined at the end of the incubation as described in Section 2. The inset shows binding of LDL at 37°C as measured as heparin-releasable radioactivity. Data are mean values from three wells. Atherosclerosis  , 13-21DOI: ( /S (00) )


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