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Lower vitamin D status is closely correlated with eczema of the head and neck  Seongmin Noh, MD, Chang Ook Park, MD, Jung Min Bae, MD, Jungsoo Lee, MD,

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Presentation on theme: "Lower vitamin D status is closely correlated with eczema of the head and neck  Seongmin Noh, MD, Chang Ook Park, MD, Jung Min Bae, MD, Jungsoo Lee, MD,"— Presentation transcript:

1 Lower vitamin D status is closely correlated with eczema of the head and neck 
Seongmin Noh, MD, Chang Ook Park, MD, Jung Min Bae, MD, Jungsoo Lee, MD, Jung U. Shin, MD, Chein-Soo Hong, MD, PhD, Kwang Hoon Lee, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 133, Issue 6, Pages e6 (June 2014) DOI: /j.jaci Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 A, Mean serum 25-hydroxyvitamin D (25[OH]VitaminD) concentrations in 49 HCs, 82 patients with AD, and 38 asthmatic patients. Patients with AD have much lower 25(OH)VitaminD concentrations than HCs (P < .001) or asthmatic patients (P = .001). B and C, The correlation study showed a statistically significant negative correlation between the 25(OH)VitaminD concentration and eczema involvement of the total area (r = −0.376, P = .001; Fig 1, B) and the head and neck area (r = −0.555, P < .001; Fig 1, C) in patients with AD. **P < .01 and ***P < ns, Not significant. Journal of Allergy and Clinical Immunology  , e6DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig E1 Mean serum 25-hydroxyvitamin D (25[OH]VitaminD) concentrations according to disease severity in 82 patients with AD (A) and 38 asthmatic patients (B). There was no significant difference in 25(OH)VitaminD concentrations according to the severity of AD or asthma. ns, Not significant. Journal of Allergy and Clinical Immunology  , e6DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4 Fig E2 Graphic analysis of correlation studies in 82 patients with AD. Correlations between 25-hydroxyvitamin D (25[OH]VitaminD) concentrations and age (A), total serum IgE level (B), eosinophil count (C), eosinophilic cationic protein level (D), EASI score (E), and eczema area of the upper limb (F), trunk (G), and lower limb (H) are shown. Spearman rho was used for analysis of eczema area, whereas other variables were analyzed with Pearson correlation. Journal of Allergy and Clinical Immunology  , e6DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5 Fig E3 Mean serum 25-hydroxyvitamin D (25[OH]VitaminD) concentrations in patients with intrinsic and extrinsic AD. There was no significant difference between AD types. ns, Not significant. Journal of Allergy and Clinical Immunology  , e6DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

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