1. Inducing Hypothermia in Neonatal/Pediatric ECMO Cases
University of Pittsburgh
Senior Design - BioE1160
December 5, 2003
Inducing Hypothermia in Neonatal/Pediatric ECMO Cases
Adam Abdulally
Erin Aghamehdi
Kim Albrecht
Rebecca Hrutkay

2. Overview
There is no means of rapidly cooling pediatric and neonatal ECMO patients.
Cooling offers a way to provide neurological protection for the patient.
Solution: A cooling unit that will work in conjunction with pediatric and neonatal ECMO circuits
Current Design Possibilities:
Cooling block
Cooling sleeve

3. Next Semester Project Goals
High-level timing goals:
January – choose design and start
modeling
February – complete computer modeling
& analysis
March – research means of building
cooling unit

4. Features & Benefits Features: Benefits: Accurate and rapid cooling
Prevention of neurological damage and patient safety
Patient temperature sensors
Ensure proper cooling
Benefits:
Inducing hypothermia when desirable
Integration into ECMO circuit
Limits amount of new equipment and pick and choose when to use it

5. Cooling Sleeve

6. Function Means Tree

7. Alternative Design

8. Competitive Analysis Competitors: Strengths: Weaknesses:
Internal cooling
Non-invasive surface cooling
Strengths:
Simple integration
No additional infused liquids
Weaknesses:
Requires constant monitoring
Limited patient range

9. Technology New technology: Engineering Models:
Novel reworking of current ideas
Engineering Models:
Solidworks
ANSYS

10. Team/Resources Resources allocated: ECMO circuit Children’s Hospital
Possible engineering mentor

11. Schedule & Milestones

12. Who is going to do what Everyone – research, modeling, testing
Kim and Rebecca – controller
Adam – heat transfer
Erin – cooling mechanisms

13. Current Status Milestones: Met w/ advisor (Dr. Carcillo)
Completed homework
Two preliminary designs
Talked to perfusionists about the project
Dr. Kameneva about biorheology and
heat transfer
Exploring thermal analysis in Ansys

14. Acknowledgements Sources of funding Dr. Carcillo Mark
Mike Schaffer – perfusionist at Children’s Hospital
Children’s ICU
Dr. Kameneva

15. Questions?