1. Aim: How does HIV affect the immune system?

2. What could have made him look so sick?

3. It is a virus that attacks our immune system.
What is HIV?
It is a virus that attacks our immune system.
How does our body know this is an enemy?
ANTIGEN

4. Passed through the placenta Open wound Sharing needles - drugs
How can we contract HIV?
Sexual intercourse
Blood transfusion
Passed through the placenta
Open wound
Sharing needles - drugs
Do phenolthalein activity

5. What part of our immune system does it attack?
White blood cells
HIV attacks special WBC’s called T-Cells

6. How are B-cells different than T-cells?
turn on
B Cells
Make
antibodies

7. How does HIV replicate? HIV attaches to a T-cell
It inserts its genetic info. into the T-cell
It makes HIV DNA
HIV hides inside the cell's DNA:
This turns the cell into a HIV factory.
HIV
Virus
T-Cell

8. Effects
You don’t die from the HIV infection, rather you die from the diseases/infections you get because your body can’t defend itself. (ex: pneumonia and skin cancer)

9. Can we make a vaccine?
It is very difficult because the virus mutates very quickly and produces different antigens after only a few generations.

10. Where is AIDS an epidemic?