1. Tiny RNA with great effects: miR-155 in alcoholic liver disease
Phillipp Hartmann, Frank Tacke 
Journal of Hepatology 
Volume 64, Issue 6, Pages (June 2016)
DOI: /j.jhep
Copyright © 2016 European Association for the Study of the Liver Terms and Conditions

2. Fig. 1
Proposed roles of microRNA-155 (miR-155) in alcoholic liver disease (ALD). In a mouse model of ALD, miR-155 was found to be upregulated in hepatocytes and liver macrophages (Kupffer cells). By comparing wild-type (WT) and miR-155-deficient (KO) mice, Bala and coworkers revealed a central functional role of miR-155 for controlling lipid metabolism in hepatocytes and pro-inflammatory (M1) polarization in macrophages, ultimately promoting steatosis, hepatitis and fibrosis.
Journal of Hepatology  , DOI: ( /j.jhep )
Copyright © 2016 European Association for the Study of the Liver Terms and Conditions