1. Date of download: 12/16/2017
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From: Biomechanics of the Posterior Eye: A Critical Role in Health and Disease
J Biomech Eng. 2014;136(2): doi: /
Figure Legend:
Histologic section through the ONH, showing the retina (R), the choroid (C), the peripapillary sclera (ppS), the lamina cribrosa (LC) (outlined in black), the post-laminar tissue of the optic nerve (pLC), and the vitreous chamber inside of the eye (VH) for (a) a normal ONH, and (b) a glaucomatous ONH. Note that the retina has artifactually separated from the choroid in some regions of the image in (a). Glaucoma is clinically characterized by the cupping of the ONH, which results from the loss of RGC axons and from thinning and the permanent posterior bowing of the LC. Scale bar: about 0.75 mm. (Reproduced with permission from Ref. [64]. Images: ARVO.)