1. Mammals use multiple DNA repair pathways of variable accuracy to repair the myriad forms of DNA damage genomic DNA is subjected to. Listed are the major types of DNA damaging agents, the DNA lesions so formed (schematized and listed), the DNA repair pathway responsible for repairing the different lesions, and the relative fidelity of these pathways. (Modified, with permission, from: “DNA-Damage Response in Tissue-Specific and Cancer Stem Cells” Cell Stem Cell 8:16-29 (2011) copyright © 2011 Elsevier Inc.
Source: Chapter 35. DNA Organization, Replication, & Repair, Harper's Illustrated Biochemistry, 29e
Citation: Murray RK, Bender DA, Botham KM, Kennelly PJ, Rodwell VW, Weil P. Harper's Illustrated Biochemistry, 29e; 2012 Available at: Accessed: December 16, 2017
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