1. Secretion of Gastric Enzymes
by Hari Mani

2. Gastric Enzymes
Enzymes that are secreted by the stomach are called gastric enzymes.
These include:
Pepsin
Gelatinase
Gastric amylase
Gastric lipase

3. Pepsin Main enzyme secreted by stomach
Secreted by the chief cells as pepsinogen
Pepsin degrades proteins into peptides
Pepsinogen is activated by hydrochloric acid (secreted by parietal cells) to form pepsin

4. Gelatinase
Proteolytic enzyme that allows a living organism to hydrolyze gelatin into its sub-compounds
These sub-compounds (polypeptides, peptides and amino acids) can then cross over the cell membrane and be utilized by the cell.

5. Gastric Amylase Enzyme that breaks down starch into sugars
This process occurs mainly in the mouth but the stomach does secrete minor amounts of amylase to continue starch degradation into di- and trisaccharides

6. Gastric Lipase
An acidic lipase that aids in the transport and processing of triglyercides, oils and fats
Secreted by chief cells in the mucosa of the gastric fundus (a portion of the left side of the stomach)
Does not require bile acid or colipase (unlike alkaline lipases, i.e. pancreatic lipase) for optimal enzymatic activity
In infants, makes up to 50% of lipase activity